Site na polyfunctionality nke carbohydrates, acid catalyzed Fischer mmeghachi omume na-enwe ọnọdụ iji mepụta ngwakọta oligomer nke na-ejikọta ihe karịrị otu glycation na microsphere mmanya. A na-akọwa nkezi ọnụ ọgụgụ nke glycose nkeji jikọrọ mmanya na-aba n'anya dị ka (nkezi) ogo polymerization (DPI. Figure2 na-egosi nkesa maka alkyl polyglycoside na DP = 1.3. Na ngwakọta a, ntinye nke onye oligomers (mono-, di-, tri-,-, glycoside) na-adabere n'ụzọ dị ukwuu na njedebe nke glucose na nkezi nke DP) polymerization bụ ihe dị mkpa na-adabere n'ókè nke glucose na nkezi nke DP. kemịkalụ anụ ahụ na ngwa nke alkyl polyglycosides Na nkesa nha nha, DP- maka ogologo alkyl nyere nke ọma na akụrụngwa ngwaahịa dị ka polarity, solubility, wdg nkesa Flory na-akọwa alkyl polyglycosides dị ka ngwakọta nke oligomer na-ekesa ọnụ ọgụgụ.
Ọdịnaya nke ụdị onye ọ bụla na ngwakọta oligomer na-ebelata na ogo polymerization na-abawanye. Nkesa oligomer nwetara site na ụdị mgbakọ na mwepụ a dabara nke ọma na nsonaazụ nyocha (lee Isi nke 3). N'okwu dị mfe, enwere ike gbakọọ nkezi ogo polymerization (DP) nke ngwakọta alkyl polyglycoside site na mole pasent pi nke ụdị oligomeric dị iche iche "i" na ngwakọta glycoside (Nyocha 2)