Site na polyfunctionality nke carbohydrates, acid catalyzed Fischer mmeghachi omume na-enwe ọnọdụ iji mepụta ngwakọta oligomer nke na-ejikọta ihe karịrị otu glycation na microsphere mmanya. A na-akọwa nkezi ọnụọgụ glycose nke jikọtara ya na otu mmanya na-aba n'anya dị ka ogo (nkezi) nke polymerization (DPI. Figure2 na-egosi nkesa maka alkyl polyglycoside na DP = 1.3. Na ngwakọta a, ntinye uche nke onye oligomers n'otu n'otu (mono- ,di-,tri-,-, glycoside) dabere na oke glucose na mmanya na ngwakọta mmeghachi omume, nkezi ogo polymerization (DP) bụ njirimara dị mkpa gbasara kemịkalụ anụ ahụ na ngwa nke alkyl polyglycosides. Na nkesa nha nha, DP- maka ogologo ogologo alkyl nyere - na-ejikọta nke ọma na ihe ndị bụ isi ngwaahịa, dị ka polarity, solubility, wdg N'ụkpụrụ, PJFlory nwere ike ịkọwa nkesa oligomer a maka ịkọwapụta nkesa oligomer nke ngwaahịa dabere na ya. Enwere ike itinye monomers polyfunctional na alkyl polyglucosides ụdị nkesa Flory a gbanwere na-akọwa alkyl polyglycosides dị ka ngwakọta nke oligomer ekesa.
Ọdịnaya nke ụdị onye ọ bụla na ngwakọta oligomer na-ebelata na ogo polymerization na-abawanye. Nkesa oligomer nwetara site na ụdị mgbakọ na mwepụ a dabara nke ọma na nsonaazụ nyocha (lee Isi nke 3). N'okwu dị mfe, enwere ike gbakọọ nkezi ogo polymerization (DP) nke ngwakọta alkyl polyglycoside site na mole pasent pi nke ụdị oligomeric dị iche iche "i" na ngwakọta glycoside (Nyocha 2)